Department of Zoology and Physiology, University of Wyoming, Laramie, WY 82071, USA.
Int Rev Neurobiol. 2011;97:305-33. doi: 10.1016/B978-0-12-385198-7.00012-6.
The balance between excitation and inhibition (E/I balance) is tightly regulated in adult cortices to maintain proper nervous system function. Disturbed E/I balance is associated with numerous neuropsychological disorders, such as autism, epilepsy and schizophrenia. The present review will discuss aspects of Hebbian and homeostatic mechanisms regulating excitatory and inhibitory balance related to sensory processing in somatosensory cortex of rodents. Additionally, changes in the E/I balance during sensory manipulation will be discussed.
兴奋与抑制（E/I 平衡）之间的平衡在成人皮质中受到严格调节，以维持神经系统的正常功能。E/I 平衡失调与许多神经心理障碍有关，如自闭症、癫痫和精神分裂症。本综述将讨论调节兴奋性和抑制性平衡的赫布（Hebbian）和动态平衡机制的各个方面，这些机制与感觉处理有关。此外，还将讨论感觉处理过程中 E/I 平衡的变化。
