骨髓增生异常综合征的发病率和患病率：杜塞尔多夫 MDS 登记处的数据。

Incidence and prevalence of myelodysplastic syndromes: data from the Düsseldorf MDS-registry.

机构信息

Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University, Düsseldorf, Germany.

出版信息

Leuk Res. 2011 Dec;35(12):1591-6. doi: 10.1016/j.leukres.2011.06.001. Epub 2011 Jun 25.

DOI:10.1016/j.leukres.2011.06.001

Abstract

Population-based data on patients with MDS are scarce. Here we report the incidence and prevalence of MDS based on data from the Düsseldorf MDS Registry. Cases in the city of Düsseldorf in the study period were identified from the MDS Registry. We calculated crude, calendar-year, age- and sex-specific and European Standard Population age-standardized incidence rates as well as point prevalences per 100,000 The crude incidence rate was 4.15/100,000/year and the point prevalence per 100,000 persons of 7. We found that the incidence and prevalence of MDS was higher in men than women and increased sharply with increasing age.

摘要

人群中 MDS 患者的数据较为匮乏。在此，我们报告了基于杜塞尔多夫 MDS 注册中心数据的 MDS 发病率和患病率。研究期间，从 MDS 注册中心确定了杜塞尔多夫市的病例。我们计算了粗发病率、日历年度发病率、年龄和性别特异性发病率以及欧洲标准人口年龄标准化发病率，以及每 10 万人的时点患病率。粗发病率为 4.15/100,000/年，每 10 万人的时点患病率为 7。我们发现，MDS 的发病率和患病率男性高于女性，且随年龄增长急剧上升。