Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 66-350, Cambridge, MA 02139, USA.
Angew Chem Int Ed Engl. 2011 Aug 8;50(33):7502-19. doi: 10.1002/anie.201004637. Epub 2011 Jun 27.
The fine chemicals and pharmaceutical industries are transforming how their products are manufactured, where economically favorable, from traditional batchwise processes to continuous flow. This evolution is impacting synthetic chemistry on all scales-from the laboratory to full production. This Review discusses the relative merits of batch and micro flow reactors for performing synthetic chemistry in the laboratory.
精细化工和制药行业正在改变其产品的制造方式,在经济有利的情况下,从传统的分批工艺转变为连续流。这种演变正在影响各个规模的合成化学,从实验室到全生产。本文综述了批处理和微流反应器在实验室进行合成化学的相对优点。