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瑜伽疗法作为精神分裂症的辅助治疗:一项随机对照的初步研究。

Yoga therapy as an adjunctive treatment for schizophrenia: a randomized, controlled pilot study.

出版信息

J Altern Complement Med. 2011 Jul;17(7):601-7. doi: 10.1089/acm.2010.0075.

DOI:10.1089/acm.2010.0075
PMID:21711202
Abstract

OBJECTIVES

There has been limited study of therapeutic yoga as a complementary treatment for schizophrenia. This study investigates the effects of a Yoga Therapy program on symptomatology and quality of life in adults with schizophrenia in a state psychiatric facility.

METHODS

In a randomized, controlled pilot study, 18 clinically stable patients (12 men and 6 women) with schizophrenia (mean age=42±13.5) were randomized to an 8-week Yoga Therapy program (YT) and a Waitlist group (WL). YT intervention included yoga postures, breathing exercises, and relaxation. At baseline and at 8 weeks, symptomatology was measured using the Positive and Negative Syndrome Scale (PANSS). Secondary efficacy outcomes were measured with the World Health Organization Quality of Life BREF questionnaire (WHOQOL-BREF).

RESULTS

The YT group obtained significant improvements in positive and negative symptoms of schizophrenia symptoms compared to WL, including PANSS scores on positive syndrome (t=-2.64, p=0.02), negative syndrome (t=-3.04, p<0.01), general psychopathology (t=-3.74, p<0.00), activation (t=-2.29, p<0.04), paranoia (t=-2.89, p<0.01), and depression subscales (t=-2.62, p<0.02). PANSS total scores also decreased for the YT group (t=-4.54, p<0.00). YT had improved perceived quality of life in physical (t=2.38, p<0.04) and psychologic domains (t=2.88, p<0.01).

CONCLUSIONS

Adults with schizophrenia being treated in a state psychiatric facility who participated in an 8-week therapeutic yoga program showed significant improvements in psychopathology and quality of life compared with controls. The findings of this study need to be confirmed in larger, more sufficiently powered studies with active control groups.

摘要

目的

针对瑜伽疗法作为精神分裂症补充疗法的研究较少。本研究调查了瑜伽疗法对州立精神病院成人精神分裂症患者症状和生活质量的影响。

方法

在一项随机、对照的初步研究中,18 名病情稳定的精神分裂症患者(12 名男性,6 名女性;平均年龄 42±13.5 岁)被随机分配到瑜伽疗法组(YT)和候补组(WL)。YT 干预包括瑜伽姿势、呼吸练习和放松。在基线和 8 周时,采用阳性和阴性综合征量表(PANSS)评估症状。次要疗效指标采用世界卫生组织生活质量简表(WHOQOL-BREF)进行测量。

结果

与 WL 组相比,YT 组精神分裂症阳性和阴性症状均显著改善,包括阳性综合征(t=-2.64,p=0.02)、阴性综合征(t=-3.04,p<0.01)、一般精神病理学(t=-3.74,p<0.00)、激活(t=-2.29,p<0.04)、偏执(t=-2.89,p<0.01)和抑郁子量表(t=-2.62,p<0.02)。YT 组 PANSS 总分也降低(t=-4.54,p<0.00)。YT 组患者在生理(t=2.38,p<0.04)和心理领域(t=2.88,p<0.01)的生活质量感知得到改善。

结论

在州立精神病院接受治疗的精神分裂症成人在参加 8 周的治疗性瑜伽项目后,与对照组相比,精神病理学和生活质量均有显著改善。需要在更大的、有充分效能的、有对照组的研究中证实这些研究结果。

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