Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, CH-3010 Bern, Switzerland.
Clin Oral Investig. 2012 Jun;16(3):755-60. doi: 10.1007/s00784-011-0583-2. Epub 2011 Jun 30.
The present study validated the accuracy of data from a self-reported questionnaire on smoking behaviour with the use of exhaled carbon monoxide (CO) level measurements in two groups of patients. Group 1 included patients referred to an oral medicine unit, whereas group 2 was recruited from the daily outpatient service. All patients filled in a standardized questionnaire regarding their current and former smoking habits. Additionally, exhaled CO levels were measured using a monitor. A total of 121 patients were included in group 1, and 116 patients were included in group 2. The mean value of exhaled CO was 7.6 ppm in the first group and 9.2 ppm in the second group. The mean CO values did not statistically significantly differ between the two groups. The two exhaled CO level measurements taken for each patient exhibited very good correlation (Spearman's coefficient of 0.9857). Smokers had a mean difference of exhaled CO values of 13.95 ppm (p < 0.001) compared to non-smokers adjusted for the first or second group. The consumption of one additional pack year resulted in an increase in CO values of 0.16 ppm (p = 0.003). The consumption of one additional cigarette per day elevated the CO measurements by 0.88 ppm (p < 0.001). Based on these results, the correlations between the self-reported smoking habits and exhaled CO values are robust and highly reproducible. CO monitors may offer a non-invasive method to objectively assess current smoking behaviour and to monitor tobacco use cessation attempts in the dental setting.
本研究通过测量两组患者呼出的一氧化碳(CO)水平,验证了一份自我报告的吸烟行为问卷数据的准确性。第 1 组包括转诊到口腔医学科的患者,而第 2 组则从日常门诊服务中招募。所有患者均填写了一份关于其当前和既往吸烟习惯的标准化问卷。此外,还使用监测仪测量了呼出的 CO 水平。第 1 组共有 121 例患者,第 2 组有 116 例患者。第 1 组的呼出 CO 平均值为 7.6ppm,第 2 组为 9.2ppm。两组的 CO 值无统计学差异。每位患者进行的两次呼出 CO 水平测量之间相关性非常好(Spearman 系数为 0.9857)。与不吸烟者相比,吸烟者的呼出 CO 值平均相差 13.95ppm(p<0.001),无论调整第 1 组还是第 2 组。每增加 1 个额外的吸烟年数,CO 值会增加 0.16ppm(p=0.003)。每天多吸一支烟,CO 测量值会升高 0.88ppm(p<0.001)。基于这些结果,自我报告的吸烟习惯与呼出 CO 值之间的相关性是稳健且高度可重复的。CO 监测仪可能提供一种非侵入性的方法,用于客观评估当前的吸烟行为,并在牙科环境中监测戒烟尝试。