Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareli Road, Lucknow 226 014, Uttar Pradesh, India.
J Clin Neurosci. 2011 Aug;18(8):1084-9. doi: 10.1016/j.jocn.2010.11.036. Epub 2011 Jun 30.
Paediatric meningiomas are rare intracranial neoplasms representing 0.4% to 4.1% of tumours in paediatric patients and 1.5% to 1.8% of all intracranial meningiomas. The goal of this study was to determine the epidemiology, clinical presentation, radiological features, morphological spectrum and treatment outcome of paediatric meningiomas. All evaluable reports of meningioma in children from 1 January 1999 to 31 December 2009 were retrieved from the database of our Department of Pathology and were assessed retrospectively. This study describes 12 patients (nine males, three females; age range, 4-18 years; mean, 12.8 years). Their age and sex distribution, presenting symptoms, neurological findings, location, neuroradiological and histopathological findings were reviewed and the results were compared with published reports. Atypical and malignant meningiomas seem to be more common in childhood and adolescence than in adulthood.
儿科脑膜瘤是罕见的颅内肿瘤，占儿科患者肿瘤的 0.4%至 4.1%，占所有颅内脑膜瘤的 1.5%至 1.8%。本研究旨在确定儿科脑膜瘤的流行病学、临床表现、影像学特征、形态学谱和治疗结果。从我们病理科的数据库中检索了 1999 年 1 月 1 日至 2009 年 12 月 31 日期间所有可评估的儿童脑膜瘤报告，并进行了回顾性评估。本研究描述了 12 例患者（9 名男性，3 名女性；年龄 4-18 岁；平均年龄 12.8 岁）。回顾了他们的年龄和性别分布、临床表现、神经学发现、位置、神经放射学和组织病理学发现，并将结果与已发表的报告进行了比较。非典型和恶性脑膜瘤在儿童和青少年中似乎比在成年中更为常见。
