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欧盟的结核-艾滋病毒负担:我们了解多少?一项监测实践和结果调查。

The burden of TB-HIV in the EU: how much do we know? A survey of surveillance practices and results.

机构信息

Tuberculosis Section, Respiratory Diseases Dep, Imperial College London, London.

出版信息

Eur Respir J. 2011 Dec;38(6):1374-81. doi: 10.1183/09031936.00198310. Epub 2011 Jun 30.

DOI:10.1183/09031936.00198310
PMID:21719488
Abstract

Information on the burden of tuberculosis (TB)-HIV co-infection is critical for the planning and evaluation of TB-HIV control and treatment strategies. This study assessed current practices in countries of the European Union (EU) and European Economic Area (EEA) for monitoring HIV co-infection in TB surveillance systems, countries' current co-infection burden and associated clinical practice. An online survey was distributed to all national TB surveillance nominated European Centre for Disease Prevention and Control contact points in the EU/EEA. We received 25 responses from 30 countries (83% response rate). Patients' HIV status was collected in 18 out of the 25 TB surveillance systems, usually via clinician reporting (16 out of 18 surveillance systems). Although most countries recommended routine testing of TB patients for HIV, the proportion actually tested varied from 5% to 90%. The burden of HIV co-infection was found to be elevated in countries with higher levels of HIV testing and higher prevalence of HIV. We suggest that TB-HIV co-infection be monitored in all EU/EEA countries to facilitate the planning and evaluation of TB-HIV control strategies. Strengthening collaboration between TB and HIV clinicians and surveillance departments, and consideration of patient confidentiality restraints would be advantageous. The level of HIV testing in TB patients is low despite national recommendations and testing should be further promoted and monitored.

摘要

结核病(TB)-艾滋病毒合并感染负担的相关信息对于规划和评估结核病-艾滋病毒控制和治疗策略至关重要。本研究评估了欧盟(EU)和欧洲经济区(EEA)国家在结核病监测系统中监测艾滋病毒合并感染的现行做法、各国目前的合并感染负担以及相关临床实践。我们向欧盟/欧洲经济区的所有国家结核病监测指定的欧洲疾病预防控制中心联络点分发了在线调查。我们从 30 个国家收到了 25 份答复(回应率为 83%)。18 个结核病监测系统中有 18 个系统收集了患者的艾滋病毒状况,通常通过临床医生报告(18 个监测系统中有 16 个)。尽管大多数国家建议对结核病患者常规进行艾滋病毒检测,但实际检测的比例从 5%到 90%不等。在艾滋病毒检测水平较高和艾滋病毒流行率较高的国家,艾滋病毒合并感染的负担较高。我们建议在所有欧盟/欧洲经济区国家监测结核病-艾滋病毒合并感染,以促进规划和评估结核病-艾滋病毒控制策略。加强结核病和艾滋病毒临床医生以及监测部门之间的合作,并考虑患者保密限制将是有利的。尽管有国家建议,但结核病患者的艾滋病毒检测水平仍然很低,应进一步推广和监测检测。

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