[The effect of exogenous prostaglandins E1 and F2 alpha on the adenosine triphosphatase activity in the ileal mucosa of rats].

The influence of exogenous PG E1 and PG F2 alpha on the Na-K- and HCO3-ATPase activities was studied in the rat ileum mucosa pretreated for 3 days with the PG biosynthesis inhibitors: indometacin, dexason, vitamin E. The blockade of the PG biosynthesis increased the activity of both ATPases. Administration of PG E1 and PG F2 alpha inhibited the activity of HCO-3--ATPase and either did not affect the Na-K-ATPase activity (PG E1) or increased it (PG F2 alpha). The prostaglandins seem to participate in the electrolyte transport processes via the ATPase activity modulation.