Lee Chang Soo, Szczesny Spencer E, Soslowsky Louis J
McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Am J Orthop (Belle Mead NJ). 2011 Mar;40(3):122-8.
Orthopedic tissues respond to mechanical loads to maintain normal homeostasis and in response to injury. As the body of work on this continues to grow, it is important to synthesize the recent studies across tissues and specialties with one another and with past studies. Hence, this review highlights the knowledge gained since 2000, with only few exceptions, concerning the effects of mechanical load and biologics on remodeling and repair of orthopedic tissue.
骨科组织会对机械负荷做出反应，以维持正常的内环境稳定，并应对损伤。随着关于这方面的研究不断增加，将近期不同组织和专业领域的研究成果相互整合，并与以往的研究进行整合变得很重要。因此，本综述着重介绍了自2000年以来（少数情况除外）关于机械负荷和生物制剂对骨科组织重塑和修复影响的研究成果。
