Melzer Rainer, Theissen Günter
Department of Genetics, Friedrich Schiller University Jena, Jena, Germany.
Methods Mol Biol. 2011;754:3-18. doi: 10.1007/978-1-61779-154-3_1.
All major processes of life depend on differential gene expression, which is largely controlled by the activity of transcription factors (TFs). In plants many TFs are encoded by members of multigene families that expanded much more dramatically during land plant evolution than during the evolution of animals and fungi. Here we review typical features such as domain structure, DNA binding, and protein interactions of TFs from some families that have contributed to the development and evolution of plant-specific structures in especially important ways. Our survey includes the MADS-domain protein family involved in specifying meristem and organ identity; YABBY proteins controlling lamina outgrowth; TCP proteins controlling floral zygomorphy and apical dominance; and finally homeodomain proteins involved in stem-cell maintenance and many other processes. Common themes as well as interesting differences between these "molecular architects of plant body plans" will become apparent.
生命的所有主要过程都依赖于差异基因表达，而差异基因表达很大程度上受转录因子（TFs）活性的控制。在植物中，许多转录因子由多基因家族的成员编码，这些家族在陆地植物进化过程中的扩张比动物和真菌进化过程中更为显著。在这里，我们综述了一些转录因子家族的典型特征，如结构域结构、DNA结合和蛋白质相互作用，这些转录因子家族以特别重要的方式促进了植物特定结构的发育和进化。我们的综述包括参与确定分生组织和器官特征的MADS结构域蛋白家族；控制叶片生长的YABBY蛋白；控制花的两侧对称和顶端优势的TCP蛋白；以及最后参与干细胞维持和许多其他过程的同源结构域蛋白。这些“植物体型规划的分子建筑师”之间的共同主题以及有趣的差异将变得明显。
