Departamento de Ingeniería Química y Química Física, Facultad de Ciencias, Universidad de Extremadura, Badajoz, Spain.
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2011;46(9):944-51. doi: 10.1080/10934529.2011.586249.
Doxycycline (Dxy) and Norfloxacin (Nfx) have been oxidized by means of different technologies of increasing complexity. Preliminary experiments showed that activated carbon adsorption (1.0 g L⁻¹) of these antibiotics (C(Antibiotic) = 5 × 10⁻⁵ M) led to a 60 and 85 % of total organic carbon (TOC) removal, however, a significant decrease in adsorption capacity was experienced after several reuses of the adsorbent. UV-C irradiation of Dxy (20 % removal in 2 h) or Nfx (90 % removal in 2 h) did not affect the initial TOC content of the solution while single ozonation (C(O₃) gas inlet concentration = 15.0 ppm) led to the instantaneous disappearance of the parent compounds while TOC conversion values in the proximity of 40 % were obtained. Complex systems based on the combination of ozone, UV-C radiation, titanium dioxide and activated carbon led to similar TOC removals of the order of 70 and 65 % for Dxy and Nfx, respectively. An attempt has been made to calculate the quantum yield and direct ozonation rate constants for doxycycline and norfloxacin. Additionally, the best systems, i.e., the O₃ and O₃/UV-C processes, have been simulated by a pseudoempirical model by considering TOC as a surrogate parameter.
强力霉素（Dxy）和诺氟沙星（Nfx）已通过不同的复杂技术进行氧化。初步实验表明，这些抗生素（C（抗生素）= 5×10⁻⁵ M）的活性炭吸附（1.0 g L⁻¹）可去除 60%和 85%的总有机碳（TOC），但吸附剂重复使用几次后，吸附能力会显著下降。紫外线-C 辐射（2 小时内去除 20%）或 Nfx（2 小时内去除 90%）不会影响溶液的初始 TOC 含量，而单一臭氧氧化（C（O₃）进气浓度= 15.0 ppm）会导致母体化合物立即消失，而接近 40%的 TOC 转化率。基于臭氧、紫外线-C 辐射、二氧化钛和活性炭结合的复杂系统分别导致 Dxy 和 Nfx 的 TOC 去除率相似，约为 70%和 65%。尝试计算了强力霉素和诺氟沙星的量子产率和直接臭氧氧化速率常数。此外，还通过考虑 TOC 作为替代参数，通过准经验模型模拟了最佳系统，即 O₃和 O₃/UV-C 工艺。
