Infectious Diseases Division, Internal Medicine Department, Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708, USA.
J Travel Med. 2011 Jul-Aug;18(4):288-91. doi: 10.1111/j.1708-8305.2011.00526.x. Epub 2011 Jun 15.
A 34-year-old Nigerian man presented with nephrotic syndrome. Renal biopsy revealed chronic membranous glomerulopathy with focal segmental sclerosis. Blood Giemsa smear contained rare Plasmodium sp. trophozoites and small subunit ribosomal RNA polymerase chain reaction amplification confirmed the presence of Plasmodium malariae. This case highlights the importance of obtaining even remote travel histories from ill immigrants and considering occult quartan malaria in patients from endemic locations with nephrotic syndrome.
一位 34 岁的尼日利亚男性患者以肾病综合征就诊。肾活检显示慢性膜性肾小球病伴局灶节段性肾小球硬化。血涂片 Giemsa 染色仅偶尔可见疟原虫滋养体，小亚基核糖体 RNA 聚合酶链反应扩增证实存在间日疟原虫。该病例强调了从患病移民中获取即使是遥远旅行史的重要性，并考虑到来自肾病综合征流行地区的隐匿性间日疟的可能性。
