Alistair Reid Venom Research Unit, Liverpool School of Tropical Medicine, Liverpool, UK.
J Proteomics. 2011 Aug 24;74(9):1768-80. doi: 10.1016/j.jprot.2011.06.019. Epub 2011 Jun 25.
Antivenom is an effective treatment of snakebite but, because of the complex interplay of fiscal, epidemiological, therapeutic efficacy and safety issues, the mortality of snakebite remains unacceptably high. Efficiently combating this high level of preventable death amongst the world's most disadvantaged communities requires the globally-coordinated action of multiple intervention programmes. This is the overall objective of the Global Snakebite Initiative. This paper describes the challenges facing the research community to develop snakebite treatments that are more efficacious, safe and affordable than current therapy.
抗蛇毒血清是一种有效的蛇伤治疗方法，但由于财政、流行病学、疗效和安全性等复杂因素的相互作用，蛇伤的死亡率仍然高得令人无法接受。要有效应对世界上最弱势群体中这种可预防的高死亡率，需要多个干预项目在全球范围内协调行动。这就是全球蛇伤倡议的总体目标。本文描述了研究界面临的挑战，即开发比现有疗法更有效、更安全、更实惠的蛇伤治疗方法。
