Khan Afaq Ahmad, Siraj Fouzia, Rai Devinder, Aggarwal Shyam
Department of Hematology, Sir Ganga Ram Hospital, New Delhi, India.
Hematol Oncol Stem Cell Ther. 2011;4(2):94-6. doi: 10.5144/1658-3876.2011.94.
Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a benign indolent disorder, characterized by enlarged lymph nodes filled with histiocytes. Extranodal involvement is uncommon. The disease rarely affects the nose and paranasal sinuses. We report a case that presented with a right nasal mass, extending into all the paranasal sinuses and right orbit without any accompanying lymphadenopathy. Because of the absence of lymphadenopathy it posed a diagnostic challenge until the pathology was confirmed on histopathological examination.
罗萨伊-多夫曼病，也称为伴有巨大淋巴结病的窦性组织细胞增多症，是一种良性惰性疾病，其特征是充满组织细胞的淋巴结肿大。结外受累并不常见。该疾病很少累及鼻子和鼻窦。我们报告一例患者，表现为右侧鼻腔肿物，延伸至所有鼻窦和右侧眼眶，无任何伴随的淋巴结病。由于没有淋巴结病，在组织病理学检查确诊病理之前，它构成了诊断挑战。
