Hawliczek R, Grunert P, Ferraz-Leite H, Alesch F
Universitätsklinik für Strahlentherapie und Strahlenbiologie Wien, Osterreich.
Strahlenther Onkol. 1990 Oct;166(10):647-9.
Methods of stereotactic target localisation are used in brachytherapy of brain tumors for many years. Since 1987 eight patients with inoperable astrocytomas grade I to III were treated at the Neurosurgical Clinic and Clinic for Radiotherapy of the University Vienna by permanent stereotactic I125-seed implantation. For that purpose a newly developed applicator was used. Preliminary results confine the low risk of operation, but the follow-up time is too short for evaluation of the treatment success. Principal problems of brain brachytherapy are discussed in the light of international data. In general, I125 brachytherapy is a useful and well tolerated way of treatment of low grade astrocytomas, the risk is low, which is especially important for children and old patients.
立体定向靶点定位方法已在脑肿瘤近距离放射治疗中应用多年。自1987年以来，维也纳大学神经外科诊所和放射治疗诊所对8例无法手术的Ⅰ至Ⅲ级星形细胞瘤患者进行了永久性立体定向碘-125粒子植入治疗。为此使用了一种新开发的施源器。初步结果显示手术风险较低，但随访时间过短，无法评估治疗效果。结合国际数据讨论了脑部近距离放射治疗的主要问题。总体而言，碘-125近距离放射治疗是治疗低级别星形细胞瘤的一种有用且耐受性良好的方法，风险较低，这对儿童和老年患者尤为重要。
