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复发性肾细胞癌表现为胃肠道出血。

Recurrent renal cell cancer presenting as gastrointestinal bleed.

机构信息

Sujith V Cherian, Subhraleena Das, Amarinder Singh Garcha, Department of Medicine, SUNY Upstate Medical University, Syracuse, NY 13210, United States.

出版信息

World J Gastrointest Oncol. 2011 Jun 15;3(6):99-102. doi: 10.4251/wjgo.v3.i6.99.

DOI:10.4251/wjgo.v3.i6.99
PMID:21731909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3124636/
Abstract

We present an unusual case of renal cell cancer (RCC) which relapsed with duodenal metastasis and unveiled itself by gastrointestinal (GI) bleeding. An 80-year old Caucasian gentleman with history of renal cell cancer status post nephrectomy 11 mo previously, presented with syncope and melena. Computed tomography scan of the abdomen revealed heterogeneous soft tissue mass in the right nephrectomy bed invading the duodenum. Upper GI endoscopic biopsy confirmed the presence of recurrent renal cell cancer. However, due to extensive metastatic disease, the patient was placed on palliative chemotherapy as surgical options were ruled out. Our case report reiterates the fact that renal cell carcinoma can recur with gastrointestinal manifestations and, although a rarity, it should be considered in a patient with a history of malignancy who presents with these symptoms.

摘要

我们报告一例肾细胞癌(RCC)的不寻常病例,该病例复发并伴有十二指肠转移,表现为胃肠道(GI)出血。一位 80 岁的白人男性,有肾细胞癌病史,已行肾切除术 11 个月,因晕厥和黑便就诊。腹部 CT 扫描显示右肾切除床有不均匀软组织肿块侵犯十二指肠。上消化道内镜活检证实存在复发性肾细胞癌。然而,由于广泛的转移疾病,患者被安置在姑息化疗,因为手术选择已被排除。我们的病例报告再次强调了肾细胞癌可以以胃肠道表现复发的事实,尽管很少见,但对于有恶性肿瘤病史并出现这些症状的患者,应考虑这种情况。

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本文引用的文献

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Metastases from renal cell carcinoma presenting as gastrointestinal bleeding: two case reports and a review of the literature.以胃肠道出血为表现的肾细胞癌转移:两例病例报告及文献复习
BMC Gastroenterol. 2007 Jan 31;7:4. doi: 10.1186/1471-230X-7-4.
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Renal cell carcinoma metastasizing to duodenum: a rare occurrence.肾细胞癌转移至十二指肠:一种罕见情况。
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Duodenal metastasis: an uncommon cause of occult small intestinal bleeding.十二指肠转移瘤:隐匿性小肠出血的罕见原因。
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Unusual upper gastrointestinal bleeding due to late metastasis from renal cell carcinoma: a case report.肾细胞癌晚期转移导致的罕见上消化道出血:一例报告
Kaohsiung J Med Sci. 2004 Mar;20(3):137-41. doi: 10.1016/S1607-551X(09)70098-1.
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Diagnosis and management of duodenal obstruction due to renal cell carcinoma.肾细胞癌所致十二指肠梗阻的诊断与处理
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Concomitant duodenal and pancreatic metastases from renal cell carcinoma: report of a case.肾细胞癌伴发十二指肠和胰腺转移:1例报告
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Diagnosis and management of massive gastrointestinal bleeding owing to duodenal metastasis from renal cell carcinoma.肾细胞癌十二指肠转移所致大量胃肠道出血的诊断与处理
J Urol. 1987 Sep;138(3):611-3. doi: 10.1016/s0022-5347(17)43275-7.