Suppr超能文献

脑出血的治疗靶点。

Treatment targets in intracerebral hemorrhage.

机构信息

Department of Neurology, University of Texas Medical School-UT Health, 6431 Fannin, MSB 7.118, Houston, TX 77030, USA.

出版信息

Neurotherapeutics. 2011 Jul;8(3):374-87. doi: 10.1007/s13311-011-0055-z.

Abstract

Intracerebral hemorrhage (ICH) imparts a higher mortality and morbidity than ischemic stroke. The therapeutic interventions that are currently available focus mainly on supportive care and secondary prevention. There is a paucity of evidence to support any one acute intervention that improves functional outcome. This chapter highlights current treatment targets for ICH based on the pathophysiology of the disease.

摘要

脑出血 (ICH) 比缺血性中风具有更高的死亡率和发病率。目前可用的治疗干预措施主要集中在支持性护理和二级预防上。缺乏证据支持任何一种改善功能预后的急性干预措施。本章根据疾病的病理生理学,强调了目前针对 ICH 的治疗靶点。

相似文献

1
Treatment targets in intracerebral hemorrhage.
Neurotherapeutics. 2011 Jul;8(3):374-87. doi: 10.1007/s13311-011-0055-z.
3
Effects of celecoxib on volumes of hematoma and edema in patients with primary intracerebral hemorrhage.
J Neurol Sci. 2009 Apr 15;279(1-2):43-6. doi: 10.1016/j.jns.2008.12.020. Epub 2009 Jan 24.
4
Update on medical and surgical management of intracerebral hemorrhage.
Rev Recent Clin Trials. 2007 Sep;2(3):174-81. doi: 10.2174/157488707781662751.
5
Early recombinant factor VIIa therapy in acute intracerebral hemorrhage: promising approach.
Neurol India. 2006 Mar;54(1):24-7. doi: 10.4103/0028-3886.24697.
6
Advances in the management of intracerebral hemorrhage.
Nat Rev Neurol. 2010 Nov;6(11):593-601. doi: 10.1038/nrneurol.2010.146. Epub 2010 Sep 28.
7
Update on intracerebral hemorrhage.
Continuum (Minneap Minn). 2012 Jun;18(3):598-610. doi: 10.1212/01.CON.0000415430.99394.3e.
8
Intracerebral hemorrhage.
Semin Neurol. 2008 Nov;28(5):657-67. doi: 10.1055/s-0028-1105974. Epub 2008 Dec 29.
10
Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death.
J Cereb Blood Flow Metab. 2004 Aug;24(8):926-33. doi: 10.1097/01.WCB.0000130866.25040.7D.

引用本文的文献

1
CCL5 mediated astrocyte-T cell interaction disrupts blood-brain barrier in mice after hemorrhagic stroke.
J Cereb Blood Flow Metab. 2024 Mar;44(3):367-383. doi: 10.1177/0271678X231214838. Epub 2023 Nov 16.
2
Mitochondrial transport in neurons and evidence for its involvement in acute neurological disorders.
Front Neurosci. 2023 Oct 12;17:1268883. doi: 10.3389/fnins.2023.1268883. eCollection 2023.
3
Development and Validation of an Automatic System for Intracerebral Hemorrhage Medical Text Recognition and Treatment Plan Output.
Front Aging Neurosci. 2022 Apr 8;14:798132. doi: 10.3389/fnagi.2022.798132. eCollection 2022.
5
Deferoxamine therapy for intracerebral hemorrhage: A systematic review.
PLoS One. 2018 Mar 22;13(3):e0193615. doi: 10.1371/journal.pone.0193615. eCollection 2018.
7
Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron.
Front Physiol. 2017 May 23;8:332. doi: 10.3389/fphys.2017.00332. eCollection 2017.
8
Minimal invasive puncture and drainage versus endoscopic surgery for spontaneous intracerebral hemorrhage in basal ganglia.
Neuropsychiatr Dis Treat. 2017 Jan 25;13:213-219. doi: 10.2147/NDT.S120368. eCollection 2017.

本文引用的文献

1
Incidence of progression or rebleeding in hypertensive intracerebral hemorrhage.
J Stroke Cerebrovasc Dis. 1991;1(3):111-6. doi: 10.1016/S1052-3057(10)80001-1. Epub 2010 May 15.
2
Stroke-related translational research.
Arch Neurol. 2011 Sep;68(9):1110-23. doi: 10.1001/archneurol.2011.99. Epub 2011 May 9.
3
Iron toxicity in mice with collagenase-induced intracerebral hemorrhage.
J Cereb Blood Flow Metab. 2011 May;31(5):1243-50. doi: 10.1038/jcbfm.2010.209. Epub 2010 Nov 24.
4
Variants at APOE influence risk of deep and lobar intracerebral hemorrhage.
Ann Neurol. 2010 Dec;68(6):934-43. doi: 10.1002/ana.22134.
5
Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review.
Neurology. 2010 Oct 12;75(15):1333-42. doi: 10.1212/WNL.0b013e3181f735e5. Epub 2010 Sep 8.
8
COL4A1 mutations as a monogenic cause of cerebral small vessel disease: a systematic review.
Stroke. 2010 Aug;41(8):e513-8. doi: 10.1161/STROKEAHA.110.581918. Epub 2010 Jun 17.
10
Advances in genomic analysis of stroke: what have we learned and where are we headed?
Stroke. 2010 Apr;41(4):825-32. doi: 10.1161/STROKEAHA.109.570523. Epub 2010 Feb 18.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验