Department of Psychiatry and Neurosciences, Graduates School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Int J Neuropsychopharmacol. 2012 Jun;15(5):681-94. doi: 10.1017/S1461145711000757. Epub 2011 May 17.
Mood is conceptualized as a long-lasting emotional state, which can have profound implications for mental and physical health. The development of neuroimaging methods has enabled significant advances towards elucidating the mechanisms underlying regulation of mood and emotion; however, our understanding of mood and emotion dysregulation in stress-related psychiatric disorders is still largely lacking. From the cognitive-affective neuroscience perspective, achieving deeper, more mechanistic understanding of mood disorders necessitates detailed understanding of specific components of neural systems involved in mood dysregulation and stabilization. In this review, we provide an overview of neural systems implicated in the development of a long-term negative mood state, as well as those related to emotion and emotion regulation, and discuss their proposed involvement in mood and anxiety disorders.
情绪被概念化为一种持久的情绪状态，它对身心健康有深远的影响。神经影像学方法的发展使得我们能够深入了解调节情绪和情感的机制；然而，我们对与应激相关的精神障碍中的情绪和情感失调的理解仍然很大程度上缺乏。从认知情感神经科学的角度来看，要更深入、更深入地了解情绪障碍，就需要详细了解参与情绪失调和稳定的神经系统的特定组成部分。在这篇综述中，我们概述了与长期负面情绪状态发展相关的神经系统，以及与情绪和情绪调节相关的神经系统，并讨论了它们在情绪和焦虑障碍中的潜在作用。
