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乳腺断层合成筛查——初步经验

Breast cancer screening with tomosynthesis--initial experiences.

作者信息

Tingberg A, Förnvik D, Mattsson S, Svahn T, Timberg P, Zackrisson S

机构信息

Department of Medical Radiation Physics, Lund University, Skåne University Hospital, Malmö, Sweden.

出版信息

Radiat Prot Dosimetry. 2011 Sep;147(1-2):180-3. doi: 10.1093/rpd/ncr296. Epub 2011 Jul 5.

Abstract

Experiences gained so far using tomosynthesis for breast cancer screening will be reported. A short summary of results from preparatory studies will also be presented. The sensitivity and specificity of breast tomosynthesis (BT) will be compared with conventional two-dimensional digital mammography (DM) for breast cancer screening in a population-based study. Over 2000 women have been examined so far with BT and DM. The BT reading is significantly more time-consuming than the DM reading. Preparatory studies have shown that BT has a higher diagnostic precision and higher accuracy of size measurements and stage determination than DM. There is potential to use lower compression force with BT compared with DM, without decreasing the diagnostic accuracy. BT might play an important role in clinical as well as screening mammography. A large-scale population-based study to investigate BT as a screening modality is underway.

摘要

本文将报告目前使用断层合成技术进行乳腺癌筛查所获得的经验。同时,还将简要介绍前期研究的结果。在一项基于人群的研究中,将比较乳腺断层合成(BT)与传统二维数字乳腺摄影(DM)用于乳腺癌筛查的敏感性和特异性。到目前为止,已有2000多名女性接受了BT和DM检查。BT读片比DM读片耗时明显更长。前期研究表明,与DM相比,BT具有更高的诊断精度、尺寸测量和分期判定准确性。与DM相比,使用BT时有可能采用较低的压迫力,而不降低诊断准确性。BT可能在临床乳腺摄影和筛查乳腺摄影中发挥重要作用。一项调查BT作为筛查方式的大规模人群研究正在进行中。

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