Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.
Am J Ther. 2011 Sep;18(5):e157-8. doi: 10.1097/MJT.0b013e3182192e70.
We hereby report a short case of 71-year-old gentleman who developed ST segment elevation myocardial infarction shortly after starting the infusion of liposomal amphotericin B for disseminated histoplasmosis. We also discuss the novel pathogenesis of specific liposomal component of amphotericin B that contributed to the acute cardiopulmonary compromise in our patient leading to subsequent myocardial infarction.
我们特此报告一例 71 岁男性患者的病例，该患者在开始使用脂质体两性霉素 B 治疗播散性组织胞浆菌病后不久发生了 ST 段抬高型心肌梗死。我们还讨论了两性霉素 B 的新型脂质体成分的发病机制，该机制导致了我们患者的急性心肺功能障碍，并随后导致了心肌梗死。
