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用两性霉素B甲酯成功治疗进行性播散性组织胞浆菌病。

Successful treatment of progressive disseminated histoplasmosis with amphotericin B methyl ester.

作者信息

Neihart R E, Hinthorn D R, Hoeprich P D, Liu C

机构信息

Division of Infectious Diseases, University of Kansas Medical Center, College of Health Sciences and Hospital, Kansas City 66103.

出版信息

Diagn Microbiol Infect Dis. 1989 Jan-Feb;12(1):17-9. doi: 10.1016/0732-8893(89)90039-4.

DOI:10.1016/0732-8893(89)90039-4
PMID:2714068
Abstract

Amphotericin B methyl ester (AME) has been used to treat fungal infections, most often those caused by Coccidioides immitis. We describe the only patient with disseminated histoplasmosis who has been treated with AME. After having had alarming reactions to amphotericin B, the patient was treated and cured with AME without adverse drug effect or later relapse.

摘要

两性霉素B甲酯(AME)已被用于治疗真菌感染,最常用于治疗由粗球孢子菌引起的感染。我们描述了唯一一位接受AME治疗的播散性组织胞浆菌病患者。该患者在对两性霉素B出现严重不良反应后,接受了AME治疗并治愈,未出现药物不良反应或后期复发。

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