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Metabolism: alcohol, DNA and disease.

作者信息

Joenje Hans

机构信息

Department of Clinical Genetics and the Cancer Center Amsterdam/VUmc Institute for Cancer and Immunology, VU University Medical Center, NL-1081 BT Amsterdam, The Netherlands.

出版信息

Nature. 2011 Jul 6;475(7354):45-6. doi: 10.1038/475045a.

DOI:10.1038/475045a
PMID:21734701
Abstract
摘要

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.Fancd2 可拮抗小鼠体内天然产生的醛类的毒性作用。
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2
The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption.酒精潮红反应:饮酒导致食管癌的一个未被认识的风险因素。
PLoS Med. 2009 Mar 24;6(3):e50. doi: 10.1371/journal.pmed.1000050.
3
Relationship between DNA lesions, DNA repair and chromosomal damage induced by acetaldehyde.乙醛诱导的DNA损伤、DNA修复与染色体损伤之间的关系。
急性接触CHO导致细胞增殖减少。
Cancers (Basel). 2021 Oct 5;13(19):4999. doi: 10.3390/cancers13194999.
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Multifaceted Fanconi Anemia Signaling.多方面的范可尼贫血信号通路。
Trends Genet. 2018 Mar;34(3):171-183. doi: 10.1016/j.tig.2017.11.006. Epub 2017 Dec 16.
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Fanconi Anemia Signaling and Cancer.范可尼贫血信号传导与癌症
Trends Cancer. 2017 Dec;3(12):840-856. doi: 10.1016/j.trecan.2017.10.005. Epub 2017 Nov 10.
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A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51.一种与RAD51显性负性突变相关的新型范可尼贫血亚型。
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Tumour Biol. 2015 Dec;36(12):9525-35. doi: 10.1007/s13277-015-3703-9. Epub 2015 Jul 1.
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Chronic alcohol consumption inhibits melanoma growth but decreases the survival of mice immunized with tumor cell lysate and boosted with α-galactosylceramide.长期饮酒会抑制黑色素瘤的生长,但会降低用肿瘤细胞裂解物免疫并用α-半乳糖神经酰胺加强免疫的小鼠的存活率。
Int Immunopharmacol. 2015 Sep;28(1):359-68. doi: 10.1016/j.intimp.2015.06.018. Epub 2015 Jun 25.
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