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Inflammatory bowel disease in pregnancy.妊娠期炎症性肠病。
World J Gastroenterol. 2011 Jun 14;17(22):2696-701. doi: 10.3748/wjg.v17.i22.2696.
2
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Inflammatory bowel diseases in pregnancy.妊娠期炎症性肠病
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The Effects of Active IBD During Pregnancy in the Era of Novel IBD Therapies.新型炎症性肠病(IBD)治疗时代孕期活动性IBD的影响
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本文引用的文献

1
Inflammatory bowel diseases and management considerations: fertility and pregnancy.炎症性肠病及其管理考量:生育与妊娠
Curr Gastroenterol Rep. 2009 Oct;11(5):395-9. doi: 10.1007/s11894-009-0059-6.
2
A population-based study of breastfeeding in inflammatory bowel disease: initiation, duration, and effect on disease in the postpartum period.一项基于人群的炎症性肠病母乳喂养研究:产后的起始、持续时间及对疾病的影响。
Am J Gastroenterol. 2009 Oct;104(10):2517-23. doi: 10.1038/ajg.2009.362. Epub 2009 Jun 23.
3
Outcomes of obstetric hospitalizations among women with inflammatory bowel disease in the United States.美国炎症性肠病女性患者产科住院治疗的结局
Clin Gastroenterol Hepatol. 2009 Mar;7(3):329-34. doi: 10.1016/j.cgh.2008.10.022. Epub 2008 Oct 30.
4
Management of the pregnant IBD patient.妊娠期炎症性肠病患者的管理
Inflamm Bowel Dis. 2008 Dec;14(12):1736-50. doi: 10.1002/ibd.20532.
5
Relapses of inflammatory bowel disease during pregnancy: in-hospital management and birth outcomes.妊娠期炎症性肠病复发:住院治疗及分娩结局
Am J Gastroenterol. 2008 May;103(5):1203-9. doi: 10.1111/j.1572-0241.2007.01756.x. Epub 2008 Apr 16.
6
Pregnancy outcomes in women with inflammatory bowel disease: a large community-based study from Northern California.炎症性肠病女性的妊娠结局:一项来自北加利福尼亚的大型社区研究。
Gastroenterology. 2007 Oct;133(4):1106-12. doi: 10.1053/j.gastro.2007.07.019. Epub 2007 Jul 25.
7
Review article: Reproduction in the patient with inflammatory bowel disease.综述文章:炎症性肠病患者的生殖情况
Aliment Pharmacol Ther. 2007 Aug 15;26(4):513-33. doi: 10.1111/j.1365-2036.2007.03397.x.
8
Medical therapy and birth outcomes in women with Crohn's disease: what should we tell our patients?克罗恩病女性的药物治疗与分娩结局:我们该如何告知患者?
Am J Gastroenterol. 2007 Jul;102(7):1414-6. doi: 10.1111/j.1572-0241.2007.01214.x.
9
Disease activity in pregnant women with Crohn's disease and birth outcomes: a regional Danish cohort study.克罗恩病孕妇的疾病活动与分娩结局:丹麦一项区域性队列研究
Am J Gastroenterol. 2007 Sep;102(9):1947-54. doi: 10.1111/j.1572-0241.2007.01355.x. Epub 2007 Jun 15.
10
Therapeutic drug use in women with Crohn's disease and birth outcomes: a Danish nationwide cohort study.克罗恩病女性的治疗性药物使用与分娩结局:一项丹麦全国性队列研究。
Am J Gastroenterol. 2007 Jul;102(7):1406-13. doi: 10.1111/j.1572-0241.2007.01216.x. Epub 2007 Apr 16.

妊娠期炎症性肠病。

Inflammatory bowel disease in pregnancy.

机构信息

Division of Gastroenterology, Vanderbilt University, Nashville, TN 37232, USA.

出版信息

World J Gastroenterol. 2011 Jun 14;17(22):2696-701. doi: 10.3748/wjg.v17.i22.2696.

DOI:10.3748/wjg.v17.i22.2696
PMID:21734776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3122257/
Abstract

Crohn's disease and ulcerative colitis affect women in their child-bearing years. Family planning has come to be a common discussion between the gastroenterologist and the inflammatory bowel disease (IBD) patient. Disease control prior to desired conception and throughout pregnancy is the most important thing to keep in mind when caring for the IBD patient. Continued medical management during pregnancy is crucial in optimizing outcomes. Studies indicate that quiescent disease prior to conception infer the best pregnancy outcomes, similar to those in the general population. Active disease prior to and during pregnancy, can lead to complications such as pre-term labor, low birth weight, and small for gestational age infants. Although there are no definitive long term effects of pregnancy on IBD, there are some limited studies that suggest that it may alter the disease course. Understanding the literature and its limitations is important in the modern era of IBD care. Educating the patient and taking a team approach with the obstetrician will help achieve successful outcomes for mother and baby.

摘要

克罗恩病和溃疡性结肠炎会影响育龄期女性。在对炎症性肠病(IBD)患者进行治疗时,生育计划已成为胃肠病学家和患者之间的常见讨论话题。在期望受孕前和整个怀孕期间控制疾病是照顾 IBD 患者时最重要的事情。在怀孕期间继续进行医学管理对于优化结果至关重要。研究表明,在怀孕前疾病处于静止状态预示着最佳的妊娠结局,与普通人群相似。在怀孕前和怀孕期间疾病活跃,可能会导致早产、低出生体重和小于胎龄儿等并发症。尽管妊娠对 IBD 没有明确的长期影响,但一些有限的研究表明,它可能会改变疾病的进程。在 IBD 护理的现代时代,了解文献及其局限性很重要。教育患者并与产科医生采取团队合作的方式,将有助于母婴获得成功的结果。