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妊娠期炎症性肠病。

Inflammatory bowel disease in pregnancy.

机构信息

Division of Gastroenterology, Vanderbilt University, Nashville, TN 37232, USA.

出版信息

World J Gastroenterol. 2011 Jun 14;17(22):2696-701. doi: 10.3748/wjg.v17.i22.2696.

Abstract

Crohn's disease and ulcerative colitis affect women in their child-bearing years. Family planning has come to be a common discussion between the gastroenterologist and the inflammatory bowel disease (IBD) patient. Disease control prior to desired conception and throughout pregnancy is the most important thing to keep in mind when caring for the IBD patient. Continued medical management during pregnancy is crucial in optimizing outcomes. Studies indicate that quiescent disease prior to conception infer the best pregnancy outcomes, similar to those in the general population. Active disease prior to and during pregnancy, can lead to complications such as pre-term labor, low birth weight, and small for gestational age infants. Although there are no definitive long term effects of pregnancy on IBD, there are some limited studies that suggest that it may alter the disease course. Understanding the literature and its limitations is important in the modern era of IBD care. Educating the patient and taking a team approach with the obstetrician will help achieve successful outcomes for mother and baby.

摘要

克罗恩病和溃疡性结肠炎会影响育龄期女性。在对炎症性肠病(IBD)患者进行治疗时,生育计划已成为胃肠病学家和患者之间的常见讨论话题。在期望受孕前和整个怀孕期间控制疾病是照顾 IBD 患者时最重要的事情。在怀孕期间继续进行医学管理对于优化结果至关重要。研究表明,在怀孕前疾病处于静止状态预示着最佳的妊娠结局,与普通人群相似。在怀孕前和怀孕期间疾病活跃,可能会导致早产、低出生体重和小于胎龄儿等并发症。尽管妊娠对 IBD 没有明确的长期影响,但一些有限的研究表明,它可能会改变疾病的进程。在 IBD 护理的现代时代,了解文献及其局限性很重要。教育患者并与产科医生采取团队合作的方式,将有助于母婴获得成功的结果。

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