循环肿瘤细胞与食管癌心脏转移：一例报告
Circulating tumor cells and cardiac metastasis from esophageal cancer: a case report.
作者信息
Consoli Francesca, Arcangeli Giuseppina, Ferrari Vittorio, Grisanti Salvatore, Almici Camillo, Bordonali Tania, Simoncini Edda
机构信息
Department of Medical Oncology, Beretta Foundation, Azienda Spedali Civili, Brescia, Italy.
出版信息
Case Rep Oncol. 2011 May;4(2):299-303. doi: 10.1159/000329021. Epub 2011 May 28.
We report the case of a 67-year-old man affected by metastatic esophageal cancer. The patient developed a symptomatic heart metastasis presenting as mimicking ST-segment elevation myocardial infarction. Cardiac magnetic resonance imaging (MRI) documented the presence of a mass in the apex and septum of the left ventriculum. The dissemination of cancer was confirmed by the detection of circulating tumor cells (CTCs) in the peripheral blood, measured by the CellSearch System (Veridex, LLC, Raritan, N.J., USA). The blood sample drawn at cardiac disease progression revealed the presence of 2 CTCs per 7.5 ml of blood. This report highlights the potential role of CTCs as markers of metastatic spread.
我们报告了一例67岁患有转移性食管癌的男性病例。该患者出现了有症状的心脏转移，表现为酷似ST段抬高型心肌梗死。心脏磁共振成像（MRI）记录显示左心室心尖和室间隔有肿块。通过CellSearch系统（美国新泽西州拉里坦市Veridex有限责任公司）检测外周血中的循环肿瘤细胞（CTC），证实了癌症的扩散。在心脏病进展时采集的血样显示，每7.5毫升血液中有2个CTC。本报告强调了CTC作为转移扩散标志物的潜在作用。
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