Wikarek Tomasz, Olszanecka-Glinianowicz Magdalena, Chudek Jerzy, Sikora Jerzy, Skałba Piotr
Zakład Promocji Zdrowia i Leczenia Otyłości, Katedry Patofizjologii Slaskiego Uniwersytetu Medycznego w Katowicach, Polska.
Ginekol Pol. 2011 Mar;82(3):205-9.
Anti-Müllerian hormone (AMH) belongs to a family of growth and differentiation factors beta (TGF-beta). In male fetuses AMH induces regression of Müller's ducts whereas in female ones this hormone plays an important role during adolescence and reproductive period. AMH participates in regulation of folliculogenesis by inhibiting the recruitment of prenatal and antral follicles. The aim of the present study was to summarize the current knowledge of the role of AMH in menstrual and fertility disturbances in obese women and those with polycystic ovary syndrome.
抗苗勒管激素(AMH)属于β生长和分化因子家族(转化生长因子-β)。在男性胎儿中,AMH诱导苗勒管退化,而在女性胎儿中,这种激素在青春期和生殖期发挥重要作用。AMH通过抑制始基卵泡和窦卵泡的募集参与卵泡发生的调节。本研究的目的是总结目前关于AMH在肥胖女性和多囊卵巢综合征患者月经和生育紊乱中作用的知识。