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[Synthetic immunogenic complexes containing a peptide from the surface protein of the foot-and-mouth disease virus].

作者信息

Rar V A, Makarov E A, Iurovskiĭ V V, Meshcheriakova E A, Andronova T M, Ivanov V T

出版信息

Bioorg Khim. 1990 Jul;16(7):904-15.

PMID:2173604
Abstract

Synthetic constructions containing a peptide antigenic determinant (C-terminal peptide 205-213 of the surface VP1 protein of the foot-and-mouth disease virus, O1K strain), glucosaminylmuramayl dipeptide (GMDP), and polyionic synthetic carriers were prepared. The polymerized peptide and peptide-BSA conjugates were synthesized as well. Among the constructions obtained only peptide-BSA conjugate proved to be highly immunogenic. Application of synthetic constructions to design immunogenic complexes is discussed.

摘要

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