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丙型肝炎:孕期是否需要进行普遍筛查?

Hepatitis C: is there a case for universal screening in pregnancy?

作者信息

Martyn F, Phelan O, O'Connell M

机构信息

Department of Obstetrics & Gynaecology, Coombe Women & Infant's University Hospital, Dolphin's Barn, Dublin 8.

出版信息

Ir Med J. 2011 May;104(5):144-6.

PMID:21736090
Abstract

Hepatitis C (HCV) is not routinely screened for antenatally in all maternity hospitals. Most hospitals adopt a policy of targeted screening. The policy in the Coombe Women and Infants University Hospital in Dublin changed from targeted screening in 2006 to universal screening in 2007. We audited the two consecutive years. The prevalence of HCV in our antenatal population was 1.4% for 2006 (67/4666) when targeted screening applied and in 2007--0.71% (66/9222) when universal screening came into affect. One woman in 2007 would not have been detected by targeted screening--1.49% (1/67). Fifty five percent (37/67) of women were HCV-RNA positive in 2006 and 57.5% (38/66) were positive in 2007. We conclude that there were similar detection rates for HCV in 2006 and 2007 and that universal screening is not required if inclusive criteria for selective screening are employed but is of use in research context.

摘要

并非所有妇产医院都会在产前对丙型肝炎(HCV)进行常规筛查。大多数医院采取的是针对性筛查政策。都柏林库姆女子及婴儿大学医院的政策在2006年从针对性筛查转变为2007年的普遍筛查。我们对这连续两年进行了审核。在我们的产前人群中,2006年采用针对性筛查时HCV的患病率为1.4%(67/4666),2007年普遍筛查生效时为0.71%(66/9222)。2007年有一名女性通过针对性筛查未能被检测出来——占2006年检测出病例的1.49%(1/67)。2006年55%(37/67)的女性HCV-RNA呈阳性,2007年这一比例为57.5%(38/66)。我们得出结论,2006年和2007年HCV的检测率相似,如果采用选择性筛查的包容性标准,则不需要普遍筛查,但在研究背景下是有用的。

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