Jarrett R F, Clark D A, Josephs S F, Onions D E
Department of Veterinary Pathology, Veterinary School, Glasgow, United Kingdom.
J Med Virol. 1990 Sep;32(1):73-6. doi: 10.1002/jmv.1890320113.
Saliva and peripheral blood samples from 20 healthy adults were examined for the presence of human herpesvirus-6 (HHV-6) DNA sequences using the polymerase chain reaction. Eighteen out of 20 whole saliva samples contained detectable HHV-6 genomes. The majority of peripheral blood samples were also positive; however, the results suggest that only a rare cell in the peripheral blood is infected. Serological studies did not reveal any correlation between HHV-6 antibody titre and the ability to detect HHV-6 DNA. The data indicate that HHV-6 genomes persist in the peripheral blood and oropharynx or salivary glands of most healthy individuals following primary infection.
使用聚合酶链反应检测了20名健康成年人的唾液和外周血样本中人类疱疹病毒6型（HHV-6）DNA序列的存在情况。20份全唾液样本中有18份含有可检测到的HHV-6基因组。大多数外周血样本也呈阳性；然而，结果表明外周血中只有极少数细胞被感染。血清学研究未发现HHV-6抗体滴度与检测HHV-6 DNA的能力之间存在任何相关性。数据表明，初次感染后，HHV-6基因组在大多数健康个体的外周血、口咽或唾液腺中持续存在。
