噬菌体疗法治疗耐药性铜绿假单胞菌尿路感染。
Bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection.
机构信息
Centre for Infectious Diseases and Microbiology, Sydney West Area Health Service, NSW 2145, Australia.
Special Phage Services Pty, Brookvale, Sydney, NSW, Australia.
出版信息
J Med Microbiol. 2011 Nov;60(Pt 11):1697-1700. doi: 10.1099/jmm.0.029744-0. Epub 2011 Jul 7.
We describe the success of adjunctive bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection in the context of bilateral ureteric stents and bladder ulceration, after repeated failure of antibiotics alone. No bacteriophage-resistant bacteria arose, and the kinetics of bacteriophage and bacteria in urine suggest self-sustaining and self-limiting infection.
我们描述了在双侧输尿管支架和膀胱溃疡的情况下，辅助噬菌体治疗难治性铜绿假单胞菌尿路感染的成功案例，此前单独使用抗生素治疗已反复失败。没有出现噬菌体耐药菌，噬菌体和尿液中的细菌动力学表明感染具有自我维持和自我限制的特征。
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