Valadbeigi Hassan, Sadeghifard Nourkhoda, Salehi Majid B
Department of Microbiology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.
Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Infect Disord Drug Targets. 2017;17(2):86-89. doi: 10.2174/1871526517666170427121956.
P. aeruginosa is one of the bacteria opportunistic that played main role in pathogenicity of patient in urinary tract infection (UTI) and respiratory tract infections. So, the aim of this study was to evaluate the prevalence of virulence genes including algD and pilA among Pseudomonas aeruginosa in urinary tract infection and tracheal isolates. After DNA extraction of clinical isolates, polymerase chain reaction was performed, and the results highlighted algD in all isolates, while pilA was dominant in tracheal isolates. We concluded that pathogenicity of urinary tract infection isolates is more than tracheal isolates, but future studies should confirm this.
铜绿假单胞菌是在尿路感染（UTI）和呼吸道感染患者致病性中起主要作用的机会性细菌之一。因此，本研究的目的是评估尿路感染和气管分离株中铜绿假单胞菌毒力基因（包括algD和pilA）的流行情况。对临床分离株进行DNA提取后，进行聚合酶链反应，结果显示所有分离株中均有algD，而pilA在气管分离株中占主导地位。我们得出结论，尿路感染分离株的致病性高于气管分离株，但未来的研究应证实这一点。
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