Department of Medicine, State University of New York Upstate Medical University, Syracuse, NY 13210, USA.
Exp Biol Med (Maywood). 2011 Aug;236(8):972-6. doi: 10.1258/ebm.2011.011067. Epub 2011 Jul 7.
The challenges of identifying and controlling emerging diseases impact individual health, as well as political, social and economic situations. In this review we discuss the role of proteomics for investigation of pathogen discovery, outbreak investigation, bio-defense, disease control, host-pathogen dynamics and vaccine development of emerging and neglected tropical diseases (NTDs). In the future the discipline of proteomics may help define multiple aspects of emerging and NTDs with respect to personalized medicine and public health.
鉴定和控制新发传染病的挑战不仅影响个人健康，还会影响政治、社会和经济状况。在这篇综述中，我们讨论了蛋白质组学在新发和被忽视热带病（NTD）的病原体发现、疫情调查、生物防御、疾病控制、宿主-病原体动态和疫苗开发研究中的作用。在未来，蛋白质组学可能有助于从个性化医疗和公共卫生的角度定义新发传染病和 NTD 的多个方面。
