Jang Eun Joo, Lee Ji Yeoun, Kim Mi Kyeong, Yoon Tae Young
Department of Dermatology, School of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea.
Ann Dermatol. 2011 Feb;23(1):98-100. doi: 10.5021/ad.2011.23.1.98. Epub 2011 Feb 28.
Warty dyskeratoma (WD) is a rare epidermal tumor that frequently arises as a papule or nodule on the head or neck of middle-aged or older persons. Histologically, it shows a cup-shaped keratin-filled invagination of an acanthotic epidermis, suprabasilar clefting with villi projecting into the clefts and acantholytic dyskeratotic cells are also present. The changes almost always involve a single hair follicle. We describe a distinctive case of WD that showed involvement of two adjoining follicles within a solitary lesion.
疣状角化不良瘤(WD)是一种罕见的表皮肿瘤,常表现为中年或老年人头颈部的丘疹或结节。组织学上,它表现为棘层肥厚的表皮呈杯状充满角蛋白的内陷,基底层上裂隙形成,并有绒毛状突起伸入裂隙内,同时还存在棘层松解性角化不良细胞。这些改变几乎总是累及单个毛囊。我们描述了一例独特的WD病例,在单个病变内显示两个相邻毛囊受累。