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Direct measurement of free radical generation in isolated rat heart by electron paramagnetic resonance spectroscopy: effect of trimetazidine.

作者信息

Maupoil V, Rochette L, Tabard A, Clauser P, Harpey C

机构信息

Laboratoire de Pharmacodynamie, Faculté de Pharmacie Dijon, France.

出版信息

Adv Exp Med Biol. 1990;264:373-6. doi: 10.1007/978-1-4684-5730-8_58.

DOI:10.1007/978-1-4684-5730-8_58
PMID:2173876
Abstract
摘要

相似文献

1
Direct measurement of free radical generation in isolated rat heart by electron paramagnetic resonance spectroscopy: effect of trimetazidine.通过电子顺磁共振波谱法直接测量离体大鼠心脏中自由基的产生:曲美他嗪的作用
Adv Exp Med Biol. 1990;264:373-6. doi: 10.1007/978-1-4684-5730-8_58.
2
Evolution of free radical formation during low-flow ischemia and reperfusion in isolated rat heart.离体大鼠心脏低流量缺血及再灌注过程中自由基形成的演变
Cardiovasc Drugs Ther. 1990 Aug;4 Suppl 4:791-5. doi: 10.1007/BF00051276.
3
[Effect of anti-angina agents on the intensity of lipid peroxidation in the myocardium and liver of rats under hyperbaric oxygenation].[抗心绞痛药物对高压氧条件下大鼠心肌和肝脏脂质过氧化强度的影响]
Farmakol Toksikol. 1988 Sep-Oct;51(5):65-8.
4
Influence of trimetazidine on deleterious effect of oxygen radical species in post-ischemic acute renal failure in the rat.
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Antilipoperoxydant effect of trimetazidine in post ischaemic acute renal failure in the rat.曲美他嗪对大鼠缺血后急性肾衰竭的抗脂质过氧化作用。
Adv Exp Med Biol. 1990;264:383-8. doi: 10.1007/978-1-4684-5730-8_60.
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Protective effect of the nitroxide tempol against the cardiotoxicity of adriamycin.
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Effect of a 5 day trimetazidine pretreatment in a model of ischemic and reperfused isolated rat heart: spin trapping experiments.曲美他嗪预处理5天对离体大鼠心脏缺血再灌注模型的影响:自旋捕捉实验
Adv Exp Med Biol. 1990;264:377-82. doi: 10.1007/978-1-4684-5730-8_59.
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Electron paramagnetic resonance spectroscopy on isolated rat heart: a technical note.
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On the detection of paramagnetic species in the adriamycin-perfused rat heart: a reappraisal.关于阿霉素灌注大鼠心脏中顺磁性物质的检测:重新评估
Biochem Biophys Res Commun. 1990 May 31;169(1):30-8. doi: 10.1016/0006-291x(90)91428-u.
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Trimetazidine as indirect antioxidant.
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Role of Trimetazidine in Ischemic Preconditioning in Patients With Symptomatic Coronary Artery Disease.曲美他嗪在有症状冠状动脉疾病患者缺血预处理中的作用
Medicine (Baltimore). 2015 Aug;94(33):e1161. doi: 10.1097/MD.0000000000001161.
2
Antipsychotic-like effect of trimetazidine in a rodent model.曲美他嗪在啮齿动物模型中的抗精神病样作用。
ScientificWorldJournal. 2013 Oct 22;2013:686304. doi: 10.1155/2013/686304. eCollection 2013.
3
Protective effects of trimetazidine on bone marrow mesenchymal stem cells viability in an ex vivo model of hypoxia and in vivo model of locally myocardial ischemia.
曲美他嗪对缺氧体外模型及局部心肌缺血体内模型中骨髓间充质干细胞活力的保护作用。
J Huazhong Univ Sci Technolog Med Sci. 2012 Feb;32(1):36-41. doi: 10.1007/s11596-012-0006-x. Epub 2012 Jan 27.
4
Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression.用曲美他嗪(1-[2,3,4-三甲氧基苄基]哌嗪)对间充质干细胞进行药理预处理可保护缺氧细胞免受氧化应激,并通过Bcl-2表达增强梗死心脏中心肌功能的恢复。
J Pharmacol Exp Ther. 2009 May;329(2):543-50. doi: 10.1124/jpet.109.150839. Epub 2009 Feb 13.
5
Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts.游离脂肪酸的不良反应与缺血后离体大鼠心脏氧化应激增加有关。
Mol Cell Biochem. 2006 Feb;283(1-2):147-52. doi: 10.1007/s11010-006-2518-9.
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Combination treatment with trimetazidine and diltiazem in stable angina pectoris.曲美他嗪与地尔硫䓬联合治疗稳定型心绞痛。
Heart. 1997 Oct;78(4):353-7. doi: 10.1136/hrt.78.4.353.
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Intracoronary trimetazidine does not improve recovery of regional function in a porcine model of repeated ischemia.
Cardiovasc Drugs Ther. 1993 Nov;7(5):801-7. doi: 10.1007/BF00878934.