土荆芥酮可纠正糖尿病大鼠模型的胆固醇和甘油三酯谱。
Thujone corrects cholesterol and triglyceride profiles in diabetic rat model.
机构信息
Department of Biological Sciences, Faculty of Science, University of Jordan, Amman 11942, Jordan.
出版信息
Nat Prod Res. 2011 Jul;25(12):1180-4. doi: 10.1080/14786419.2010.496116.
Thujone, which is the major constituent in Salvia sp. (Lamiaceae), was found to correct the lipid profile (cholesterol and triglycerides) in diabetic rats. Oral treatment with thujone (5 mg kg⁻¹ body weight dose) significantly adjusted cholesterol and triglyceride levels in diabetic rats (p ≤ 0.05) to normal levels compared to diabetic untreated rats. This provides a premise in the field of finding new agents to treat diabetic complications.
荆芥酮是唇形科鼠尾草属（Salvia sp.）的主要成分，研究发现它可以纠正糖尿病大鼠的脂质谱（胆固醇和甘油三酯）。与未治疗的糖尿病大鼠相比，荆芥酮（5mg/kg 体重剂量）的口服治疗可显著调节糖尿病大鼠的胆固醇和甘油三酯水平（p≤0.05），使其恢复正常水平。这为寻找治疗糖尿病并发症的新药物提供了前提。
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