Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, 100193 Beijing, China.
Chemosphere. 2011 Aug;84(7):908-12. doi: 10.1016/j.chemosphere.2011.06.013. Epub 2011 Jul 7.
The Quick Easy Cheap Effective Rugged and Safe multiresidue method (QuEChERS) has been validated for the extraction of 15 organochlorine pesticides (OCPs) in completely different matrices of traditional Chinese medicine (TCM). The method employed a rapid, simple and cost-effective procedure. The spiking levels for the recovery experiments were 0.1, 0.5 and 2.0 mg kg(-1). Mean recoveries mostly ranged between 76.0% and 114.0% (96.0% on average), and relative standard deviations (RSD) were generally below 10% (4.72% on average). Based on these results, the methodology has been proven to be highly efficient and robust and thus suitable for monitoring the MRL compliance of a wide range of commodity. The contamination status of 15 OCPs on 80 different TCMs marketed in China, and a total of 400 samples were also performed using a previously validated method. 15 OCPs were benzene hexachloride (BHC, including α-BHC, β-BHC, γ-BHC, δ-BHC), hexachlorobenzene, heptachlor, heptachlor epoxide, aldrin, p, p'-DDE, p, p'-DDD, o, p'-DDT, p, p'-DDT, mirex, endrin, dieldrin. This study indicates that the proposed method is useful for analyzing OCPs in TCM.
快速、简单、经济、有效、耐用、安全的多残留方法（QuEChERS）已被验证可用于提取完全不同基质的中药材中 15 种有机氯农药（OCPs）。该方法采用快速、简单、经济有效的程序。加标水平为 0.1、0.5 和 2.0mgkg（-1）。回收率实验的平均回收率大多在 76.0%至 114.0%之间（平均为 96.0%），相对标准偏差（RSD）通常低于 10%（平均为 4.72%）。基于这些结果，该方法已被证明具有高效、稳健的特点，因此适用于监测广泛商品的 MRL 合规性。使用先前验证的方法，还对中国市场上 80 种不同中药材中的 15 种 OCP 进行了污染状况调查，共采集了 400 个样本。15 种 OCP 包括六六六（BHC，包括α-BHC、β-BHC、γ-BHC、δ-BHC）、六氯苯、七氯、七氯环氧、艾氏剂、p，p'-DDE、p，p'-DDD、o，p'-DDT、p，p'-DDT、灭蚁灵、异狄氏剂、狄氏剂。本研究表明，该方法可用于分析中药材中的 OCPs。
