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阿片类药物依赖患者的延迟折扣、冲动性和成瘾严重程度。

Delay discounting, impulsiveness, and addiction severity in opioid-dependent patients.

机构信息

Division of Social & Behavioral Sciences, Arizona State University, Glendale, AZ 85306-4908, USA.

出版信息

J Subst Abuse Treat. 2011 Dec;41(4):354-62. doi: 10.1016/j.jsat.2011.05.003. Epub 2011 Jul 7.

Abstract

Individuals who abuse drugs show higher delay discounting (DD) rate and impulsiveness scores compared with controls; however, it is unclear if DD rate covaries with severity of the addiction or if an individual's discounting rate can be changed by effective substance abuse treatment. This study compared methadone maintenance treatment (MMT) patients (n = 30) who had not used illegal drugs for 2 years with drug-using MMT patients (n = 30) and controls (n = 25) in terms of addiction severity, DD rate, and impulsiveness. Methadone patients abstinent from illegal drugs scored significantly lower on a number of addiction severity measures than the drug-using methadone patients. In addition, both groups of MMT patients showed significantly higher rates of DD and impulsiveness than the control group; however, no differences in DD rate or impulsiveness were found between the groups of patients. Results suggest that DD rate and impulsiveness may not covary with indicators of addiction severity in MMT patients.

摘要

与对照组相比,滥用药物的个体表现出更高的延迟折扣率(DD)和冲动性评分;然而,目前尚不清楚 DD 率是否与成瘾的严重程度相关,或者个体的折扣率是否可以通过有效的药物滥用治疗来改变。本研究比较了美沙酮维持治疗(MMT)患者(n=30,已戒断非法药物 2 年)、使用美沙酮的 MMT 患者(n=30)和对照组(n=25)的成瘾严重程度、DD 率和冲动性。与使用美沙酮的药物滥用患者相比,已戒断非法药物的美沙酮患者在多项成瘾严重程度指标上的得分明显较低。此外,两组 MMT 患者的 DD 率和冲动性明显高于对照组;然而,两组患者之间未发现 DD 率或冲动性存在差异。结果表明,DD 率和冲动性可能与 MMT 患者的成瘾严重程度指标不相关。

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