Unité de Neuropsychologie, CM2R, Service de Neurologie, CHU Nord, Saint-Etienne, France.
Epilepsy Behav. 2011 Aug;21(4):367-72. doi: 10.1016/j.yebeh.2011.06.001. Epub 2011 Jul 13.
We examined whether anxiodepressive patients with left temporal lobe epilepsy could be differentiated from those with depression but without epilepsy on tasks that investigate attentional bias toward and explicit judgment of emotional stimuli. Eight depressive patients, eight anxiodepressive patients with epilepsy, and eight controls participated in the present study. Anxiodepressive with epilepsy and depressive patients had comparable depression scores and the same cognitive profile. Two distinct emotional tasks were used: the decision lexical task and the number comparison task. Three emotional connotations were presented: neutral, positive, and negative. The pattern of results showed an attentional bias toward negative words and pictures in depressive patients and only toward negative words in anxiodepressive patients with epilepsy. Moreover, depressive patients explicitly judged negative stimuli with lower intensity and anxiodepressive patients judged neutral stimuli with higher intensity. The present study specifies the emotional functioning in depression with or without left temporal lobe epilepsy.
我们研究了左颞叶癫痫伴发抑郁的患者是否能在情绪刺激的注意偏向和外显判断任务上与不伴发癫痫的抑郁患者相区分。八位抑郁患者、八位伴发癫痫的抑郁焦虑患者以及八位对照者参与了本研究。伴发癫痫的抑郁焦虑患者和抑郁患者的抑郁评分和认知模式相当。两个不同的情绪任务被使用：决策词汇任务和数字比较任务。三个情绪含义被呈现：中性、积极和消极。结果模式表明抑郁患者对消极单词和图片存在注意偏向，而伴发癫痫的抑郁焦虑患者仅对消极单词存在注意偏向。此外，抑郁患者对外显地判断消极刺激的强度较低，而伴发癫痫的抑郁焦虑患者对中性刺激的判断强度较高。本研究明确了左颞叶癫痫伴发或不伴发抑郁患者的情绪功能。
