Preglej Lidija, Marinković Ksenija, Hećimović Hrvoje
The Accredited Private Classical High School, Zagreb, Croatia; University of Zagreb, Croatia.
Department of Psychology, San Diego State University, San Diego, CA, United States; Department of Radiology, University of California at San Diego, San Diego, CA, United States.
Epilepsy Behav. 2017 Sep;74:87-93. doi: 10.1016/j.yebeh.2017.06.030. Epub 2017 Jul 18.
In healthy people, a preference in attention maintenance and memory for words with emotional valence comparing to neutral words has been shown. The pattern of emotional stimuli processing may be different in people with mesial temporal lobe epilepsy (MTLE) and it may be sensitive to the presence of depressive symptoms. In order to explore these possibilities, we applied the emotional spatial cueing attentional task and the free recall memory task to participants (N=39) with MTLE and compared them with healthy controls. We hypothesized that the pattern of maintaining attention and remembering emotional words is different in people with MTLE. Current literature indicates that this pattern will change from positive bias in the controls, though no emotional bias in the participants with MTLE without depression (MTLE-d), and in this work we examined this pattern in the participants with MTLE with depressive symptoms (MTLE+d). Our results show that in both attention and memory, control subjects exhibit positive emotional bias, the subjects with MTLE-d show nonemotional bias and the subjects with MTLE+d have bias away from positive words. Participants with MTLE+d maintained attention for positive words shorter than others. Participants with MTLE+d had worse recall for positive words than the participants with MTLE-d and for all words when compared to controls. We found that faster attention disengagement from positive words and worse memory for positive words is associated with elevated levels of depressive symptoms.
在健康人群中，与中性词相比，对具有情感效价的词在注意力维持和记忆方面存在偏好。内侧颞叶癫痫（MTLE）患者对情感刺激的处理模式可能不同，并且可能对抑郁症状的存在敏感。为了探究这些可能性，我们对MTLE患者（N = 39）应用了情感空间线索注意任务和自由回忆记忆任务，并将他们与健康对照组进行比较。我们假设MTLE患者在维持注意力和记忆情感词方面的模式不同。当前文献表明，这种模式将从对照组的积极偏向转变，MTLE无抑郁患者（MTLE-d）没有情感偏向，在这项研究中我们研究了MTLE伴抑郁症状患者（MTLE+d）的这种模式。我们的结果表明，在注意力和记忆方面，对照组表现出积极的情感偏向，MTLE-d患者表现出无情感偏向，MTLE+d患者则远离积极词偏向。MTLE+d患者对积极词的注意力维持时间比其他人短。与MTLE-d患者相比，MTLE+d患者对积极词的回忆更差，与对照组相比，对所有词的回忆也更差。我们发现，从积极词上更快地脱离注意力以及对积极词的记忆更差与抑郁症状水平升高有关。
