Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.
Bioinformatics. 2011 Sep 1;27(17):2471-2. doi: 10.1093/bioinformatics/btr395. Epub 2011 Jul 8.
Manual curation and validation of large-scale biological pathways are required to obtain high-quality pathway databases. In a typical curation process, model validation and model update based on appropriate feedback are repeated and requires considerable cooperation of scientists. We have developed a CSO (Cell System Ontology) validator to reduce the repetition and time during the curation process. This tool assists in quickly obtaining agreement among curators and domain experts and in providing a consistent and accurate pathway database.
The tool is available on http://csovalidator.csml.org.
为了获得高质量的通路数据库，需要对大规模的生物通路进行人工注释和验证。在典型的注释过程中，需要根据适当的反馈重复进行模型验证和模型更新，这需要科学家们进行大量的合作。我们开发了一个 CSO（细胞系统本体论）验证器，以减少注释过程中的重复和时间。该工具有助于快速获得注释人员和领域专家的一致意见，并提供一致和准确的通路数据库。
该工具可在 http://csovalidator.csml.org 上获得。
