Department of Ophthalmology,California Pacific Medical Center, San Francisco, CA 94115, USA.
Ophthalmic Plast Reconstr Surg. 2012 Jan-Feb;28(1):e11-3. doi: 10.1097/IOP.0b013e3182127cb5.
Merkel cell carcinoma is a rare neuroendocrine carcinoma that most often arises in sun-exposed skin. Primary Merkel cell carcinoma of the lacrimal gland is exceedingly rare, with only one prior case reported in the literature. The authors present a 49-year-old woman with a 6-month history of painless swelling of the left upper eyelid. MRI showed a lacrimal gland mass. Surgical excision was performed, and histologic evaluation revealed a Merkel cell carcinoma. Virology testing was positive for Merkel cell polyomavirus. The patient was treated with local radiation following surgical excision. She has had no recurrence after 1 year of follow up.
默克尔细胞癌是一种罕见的神经内分泌癌，最常发生于暴露于阳光的皮肤。泪腺原发的默克尔细胞癌极为罕见，文献中仅有一例报道。作者报告了一例 49 岁女性，6 个月来左眼上睑无痛性肿胀。MRI 显示泪腺肿块。行手术切除，组织学评估显示为默克尔细胞癌。病毒学检测默克尔细胞多瘤病毒阳性。患者在手术切除后接受局部放疗。随访 1 年后无复发。
