T.S. Sathyanarayana Rao, MD, DPM, Associate Professor & Head, Department of Psychiatry, J.S.S. Medical College & Hospital, Ramanuja Road, Mysore - 570 004.
Indian J Psychiatry. 1993 Apr;35(2):127-30.
A study on the genetics of effective disorder was carried out using pedigree methodology. Ike index case presented with features of bulimia which was diagnosed to be Bipolar affective disorder. The pedigree was analyzed for 4 generations and included evaluation of 76 individuals, of whom the oldest was 103 years of age. The evaluation was done clinically to demonstrate various concepts concerning affective syndromes, the presence and extent of gene borne influences and mode of inheritance. Data was compared with other genetic research studies and suggestions for further research arc made.
采用家系研究方法对有效障碍的遗传学进行了研究。伊克索引病例表现出贪食症的特征,被诊断为双相情感障碍。对包括 76 名个体的 4 代家系进行了分析,其中最年长的为 103 岁。通过临床评估展示了各种有关情感综合征、基因影响的存在和程度以及遗传方式的概念。将数据与其他遗传研究进行了比较,并提出了进一步研究的建议。