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情感障碍的遗传学-家系研究。

The genetics of affective disorder - a pedigree study.

机构信息

T.S. Sathyanarayana Rao, MD, DPM, Associate Professor & Head, Department of Psychiatry, J.S.S. Medical College & Hospital, Ramanuja Road, Mysore - 570 004.

出版信息

Indian J Psychiatry. 1993 Apr;35(2):127-30.

PMID:21743618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2978468/
Abstract

A study on the genetics of effective disorder was carried out using pedigree methodology. Ike index case presented with features of bulimia which was diagnosed to be Bipolar affective disorder. The pedigree was analyzed for 4 generations and included evaluation of 76 individuals, of whom the oldest was 103 years of age. The evaluation was done clinically to demonstrate various concepts concerning affective syndromes, the presence and extent of gene borne influences and mode of inheritance. Data was compared with other genetic research studies and suggestions for further research arc made.

摘要

采用家系研究方法对有效障碍的遗传学进行了研究。伊克索引病例表现出贪食症的特征,被诊断为双相情感障碍。对包括 76 名个体的 4 代家系进行了分析,其中最年长的为 103 岁。通过临床评估展示了各种有关情感综合征、基因影响的存在和程度以及遗传方式的概念。将数据与其他遗传研究进行了比较,并提出了进一步研究的建议。

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本文引用的文献

1
Depressive disease: a genetic study.抑郁症:一项遗传学研究。
Arch Gen Psychiatry. 1971 Feb;24(2):135-44. doi: 10.1001/archpsyc.1971.01750080039006.
2
Morbidity risk and genetic transmission in manic-depressive illness.躁郁症的发病风险与遗传传递
Am J Hum Genet. 1974 Nov;26(6):692-701.
3
Assessing the role of X-linked inheritance in bipolar-related major affective disorder.评估X连锁遗传在双相情感障碍相关的重度情感障碍中的作用。
J Psychiatr Res. 1986;20(4):275-88. doi: 10.1016/0022-3956(86)90031-2.
4
Genetic linkage between X-chromosome markers and bipolar affective illness.X染色体标记与双相情感障碍之间的遗传连锁
Nature. 1987;326(6110):289-92. doi: 10.1038/326289a0.
5
Variable number of tandem repeat (VNTR) markers for human gene mapping.用于人类基因图谱绘制的可变串联重复序列(VNTR)标记
Science. 1987 Mar 27;235(4796):1616-22. doi: 10.1126/science.3029872.
6
Bipolar affective disorders linked to DNA markers on chromosome 11.双相情感障碍与11号染色体上的DNA标记有关。
Nature. 1987;325(6107):783-7. doi: 10.1038/325783a0.
7
X-chromosome markers and manic-depressive illness. Rejection of linkage to Xq28 in nine bipolar pedigrees.X染色体标记与躁郁症。九个双相谱系中与Xq28连锁关系的排除。
Arch Gen Psychiatry. 1990 Apr;47(4):366-73. doi: 10.1001/archpsyc.1990.01810160066010.