Harada H, Nakajima T, Inazawa J, Abe T
Department of Neuropsychiatry, Kyoto Prefectural University of Medicine, Japan.
Biol Psychiatry. 1995 Apr 1;37(7):477-9. doi: 10.1016/0006-3223(94)00172-Y.
A family suggesting cosegregation of beta-thalassemia minor and bipolar affective disorder was reported. The monogenic hereditary anemia was surveyed over three generations in this family, and three patients with the beta-thalassemia and the bipolar affective disorder were observed over two generations. The localization of a gene responsible for bipolar affective disorder was discussed on the basis of previous reports.
有报道称一个家族中轻度β地中海贫血与双相情感障碍存在共分离现象。对该家族三代人进行了单基因遗传性贫血调查，在两代人中观察到3例患有β地中海贫血和双相情感障碍的患者。根据既往报道对双相情感障碍相关基因的定位进行了讨论。
