双相情感障碍与11号染色体上的DNA标记有关。
Bipolar affective disorders linked to DNA markers on chromosome 11.
作者信息
Egeland J A, Gerhard D S, Pauls D L, Sussex J N, Kidd K K, Allen C R, Hostetter A M, Housman D E
出版信息
Nature. 1987;325(6107):783-7. doi: 10.1038/325783a0.
DOI:10.1038/325783a0
PMID:2881209
Abstract
An analysis of the segregation of restriction fragment length polymorphisms in an Old Order Amish pedigree has made it possible to localize a dominant gene conferring a strong predisposition to manic depressive disease to the tip of the short arm of chromosome 11.
摘要
对一个旧秩序阿米什人谱系中限制性片段长度多态性分离情况的分析，使得将一个赋予躁郁症强烈易感性的显性基因定位到11号染色体短臂末端成为可能。
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