Reid E K, Norris S A, Taylor J A, Hathaway E N, Smith A J, Yttri E A, Thach W T
Department of Anatomy and Neurobiology, Washington University School of Medicine, Campus Box 8108, 660 South Euclid Avenue, Saint Louis, Missouri, 63110, USA.
Curr Trends Neurol. 2009 Jan 1;3:15-22.
The anatomical connections of the parvocellular red nucleus (RNp) have led to the suggestion that it might participate along with the cerebellum in modifying old and developing new programs for the control of complex, compound, coordinated movements of multiple body parts. RNp projects to and excites the inferior olivary nuclear neurons, which send climbing fibers to excite neurons in contralateral cerebellar cortex and nuclei. RNp receives excitatory inputs from ipsilateral cerebral cortex (onto distal dendrites) and from contralateral cerebellar nuclei (onto proximal dendrites). We here further develop a hypothesis as to mechanism, and offer preliminary evidence from RNp inactivation studies in awake, trained macaques during modification of their gaze-reach calibration while wearing wedge prism spectacles.
小细胞红核（RNp）的解剖学联系表明，它可能与小脑一起参与修改旧的运动程序，并为控制多个身体部位的复杂、复合、协调运动开发新的程序。RNp投射到下橄榄核神经元并使其兴奋，下橄榄核神经元发出攀缘纤维以兴奋对侧小脑皮质和核团中的神经元。RNp从同侧大脑皮质（投射到远端树突）和对侧小脑核团（投射到近端树突）接收兴奋性输入。我们在此进一步阐述一种关于机制的假说，并提供在清醒、经过训练的猕猴佩戴楔形棱镜眼镜修改其注视-够物校准期间进行RNp失活研究的初步证据。
