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难治性慢性鼻-鼻窦炎中的骨炎。

Osteitic bone in recalcitrant chronic rhinosinusitis.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Academic Medical Centre (AMC), Amsterdam, the Netherlands.

出版信息

Rhinology. 2011 Jun;49(2):139-47. doi: 10.4193/Rhino10.158.

Abstract

INTRODUCTION

There is increasing interest in the underlying bone of the paranasal sinuses as an important player in recalcitrant Chronic Rhinosinusitis. Close inspection of CT scans often reveals areas of increased bone density and irregular thickening of the sinus walls. This osteitic bone could at least partly explain, why inflammation of the mucosa persists.

METHODS

We searched PubMed for all relevant studies, using the following text words: chronic rhinosinusitis, sinusitis, bone, osteitis, osteomyelitis, histology, and treatment. Cited references of retrieved articles were also examined.

RESULTS

Background, available data, potential diagnostic options, treatment implications, and suggestions for future research are discussed.

CONCLUSION

Osteitis is associated with CRS, however its role in the pathogenic process is not well defined. More research is needed.

摘要

简介

人们对鼻窦的骨基础越来越感兴趣,认为其是难治性慢性鼻-鼻窦炎的一个重要因素。仔细观察 CT 扫描,经常会发现骨密度增加和鼻窦壁不规则增厚的区域。这种骨炎至少可以部分解释为什么黏膜炎症持续存在。

方法

我们使用以下文字词在 PubMed 上搜索所有相关研究:慢性鼻-鼻窦炎、鼻窦炎、骨、骨炎、骨髓炎、组织学和治疗。还检查了检索文章的引用参考文献。

结果

讨论了背景、现有数据、潜在的诊断选择、治疗意义以及对未来研究的建议。

结论

骨炎与 CRS 相关,但在发病机制中的作用尚未明确。需要进一步研究。

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