State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
J Org Chem. 2011 Aug 5;76(15):6350-5. doi: 10.1021/jo200672w. Epub 2011 Jul 11.
The 1-benzoxepine derivatives were synthesized conveniently by cationic palladium-catalyzed [5 + 2] annulation reaction of 2-acylmethoxyarylboronic acids with allenoates in high yields. This annulation involves the intramolecular nucleophilic addition to ketones without the formation of π-allylpalladium species.
1-苯并氧杂环戊烯衍生物可通过 2-酰基甲氧基芳基硼酸与丙二烯酸酯的阳离子钯催化的[5+2]环加成反应以高产率方便地合成。该环加成反应涉及到酮的分子内亲核加成，而没有形成π-烯丙基钯物种。
