Ramelli G P, Marone C, Truniger B
Medizinische Klinik, Kantonsspital Luzern.
Schweiz Med Wochenschr. 1990 Oct 27;120(43):1590-4.
Overt renal disease is a rare complication of infectious mononucleosis (MI). In contrast, up to 16% of patients with MI have been shown to exhibit abnormalities in urinary sediment. Histological abnormalities--usually interstitial nephritis, and occasionally glomerular lesions--are rather common. Clinical symptoms include in rare cases isolated macrohematuria, occasionally a nephrotic or nephritic syndrome, and more commonly acute renal failure due to rhabdomyolysis, hepatorenal syndrome or acute interstitial nephritis. We report two observations of acute renal failure with a typically benign course and discuss these observations in the light of an updated literature survey of 34 patients.
显性肾病是传染性单核细胞增多症(MI)的一种罕见并发症。相比之下,高达16%的MI患者尿液沉渣显示异常。组织学异常——通常为间质性肾炎,偶尔为肾小球病变——相当常见。临床症状在罕见情况下包括孤立性肉眼血尿,偶尔为肾病综合征或肾炎综合征,更常见的是因横纹肌溶解、肝肾综合征或急性间质性肾炎导致的急性肾衰竭。我们报告了两例急性肾衰竭的观察病例,其病程通常为良性,并根据对34例患者的最新文献综述对这些观察病例进行讨论。