传染性单核细胞增多症继发急性间质性肾炎。

Acute interstitial nephritis secondary to infectious mononucleosis.

作者信息

Verma N, Arunabh S, Brady T M, Charytan C

机构信息

Department of Internal Medicine & Nephrology, The New York Hospital Medical Center of Queens, Flushing 11355, USA.

出版信息

Clin Nephrol. 2002 Aug;58(2):151-4. doi: 10.5414/cnp58151.

DOI:10.5414/cnp58151

PMID:12227688

Abstract

Renal involvement in infectious mononucleosis (IM) is infrequent. In most cases it is self-limited and is rarely associated with loss of renal function. The purpose of this case report is to document a case of acute interstitial nephritis (AIN) leading to acute renal failure (ARF) in a patient with Epstein-Barr virus (EBV) infection and to review literature of EBV infection and its renal manifestation. The patient was managed with hemodialysis and steroids and made an uneventful recovery. Renal involvement in IM may be more common than generally appreciated and may occasionally lead to ARF. Therapy with corticosteroids may have role in the management of IM-induced ARF and may shorten the duration of renal failure.

摘要

传染性单核细胞增多症（IM）累及肾脏的情况并不常见。在大多数情况下，它是自限性的，很少与肾功能丧失相关。本病例报告的目的是记录1例由爱泼斯坦-巴尔病毒（EBV）感染导致急性肾衰竭（ARF）的急性间质性肾炎（AIN）病例，并回顾EBV感染及其肾脏表现的相关文献。该患者接受了血液透析和类固醇治疗，康复过程顺利。IM累及肾脏可能比普遍认为的更为常见，偶尔可能导致ARF。皮质类固醇治疗可能在IM所致ARF的管理中发挥作用，并可能缩短肾衰竭的持续时间。