Seijo Alfredo, Morales Alejandra, Poustis Gladys, Romer Yamila, Efron Ernesto, Vilora Guillermo, Lloveras Susana, Giamperetti Sergio, Puente Teresita, Monroig Jessica, Luppo Victoria, Enría Delia
Hospital de Enfermedades Infecciosas Francisco J. Muñiz, Buenos Aires, Argentina.
Medicina (B Aires). 2011;71(3):211-7.
We describe the epidemiological and clinical findings of 13 patients with diagnosis of infection by St. Louis encephalitis virus, transmitted between January and March 2010 in Buenos Aires Metropolitan Area (AMBA). Thirteen patients, average age 38 years, had an acute onset with hyperthermia and headache. Between days two and ten of the onset of symptoms, 7/13 patients had signs and symptoms of neurological involvement. This was characterized by meningitis without encephalic sings in 1/7 and in 6/7 the most frequent findings were: stiff neck, disorientation, photophobia, confusion and language impairment. Two MR and one EEG revealed signs of involvement of temporal lobes. The cerebrospinal fluid showed pleocytosis with predominance of mononuclear cells, normal glucose and moderately elevated protein. There were no fatalities cases. In 6/13 patients the initial clinical suspicion was dengue. As epidemic virus circulation had not been previously reported in the AMBA it can be considered an outbreak of St. Louis encephalitis for the spatial and temporal clustering of cases.
我们描述了2010年1月至3月在布宜诺斯艾利斯大都市区（AMBA）传播的13例诊断为圣路易斯脑炎病毒感染患者的流行病学和临床发现。13例患者，平均年龄38岁，急性起病，伴有高热和头痛。在症状出现后的第2天至第10天，13例患者中有7例出现神经受累的体征和症状。其中1/7表现为无脑病体征的脑膜炎，6/7最常见的表现为：颈部僵硬、定向障碍、畏光、意识模糊和语言障碍。2例磁共振成像（MR）和1例脑电图显示颞叶受累迹象。脑脊液显示细胞增多，以单核细胞为主，葡萄糖正常，蛋白质中度升高。无死亡病例。13例患者中有6例最初临床怀疑为登革热。由于此前AMBA地区未报告过该流行病毒的传播，鉴于病例在空间和时间上的聚集性，可将此次事件视为圣路易斯脑炎的一次暴发。
