通道门在哪里？BK（Ca）通道深孔中的门控。 - Suppr

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超能文献

Where's the gate? Gating in the deep pore of the BK(Ca) channel.

作者信息

Cox Daniel H, Hoshi Toshinori

出版信息

J Gen Physiol. 2011 Aug;138(2):133-6. doi: 10.1085/jgp.201110681. Epub 2011 Jul 11.

DOI:10.1085/jgp.201110681

PMID:21746844

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3149440/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d51/3149440/23416dfa6fd9/JGP_201110681_RGB_Fig1.jpg

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本文引用的文献

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Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region.半胱氨酸扫描和修饰揭示了内孔区域 BK 通道和 Kv 通道之间的主要差异。

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12161-6. doi: 10.1073/pnas.1104150108. Epub 2011 Jul 5.

Low resistance, large dimension entrance to the inner cavity of BK channels determined by changing side-chain volume.BK 通道内腔小尺寸、低电阻入口由侧链体积变化决定。

J Gen Physiol. 2011 Jun;137(6):533-48. doi: 10.1085/jgp.201110616. Epub 2011 May 16.

Structural mechanism of C-type inactivation in K(+) channels.钾离子通道 C 型失活的结构机制。

Nature. 2010 Jul 8;466(7303):203-8. doi: 10.1038/nature09153.

Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution.人类 BK 通道钙激活装置的结构在 3.0A 分辨率下。

Science. 2010 Jul 9;329(5988):182-6. doi: 10.1126/science.1190414. Epub 2010 May 27.

Principles of conduction and hydrophobic gating in K+ channels.K+ 通道的传导和疏水性门控原理。

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5833-8. doi: 10.1073/pnas.0911691107. Epub 2010 Mar 15.

Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine.CTX、IbTX、TEA、4-AP 和奎尼丁对小鼠 slo1 和 slo3 K+通道的阻断作用。

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